The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2026

Filed:

Apr. 19, 2022
Applicant:

Shanghai Yao Yuan Biotechnology Co., Ltd., Shanghai, CN;

Inventors:

Yuning Wei, Shanghai, CN;

Danyang Liu, Shanghai, CN;

Cong Xu, Shanghai, CN;

Lawrence S. Melvin, Jr., Shanghai, CN;

Xiong Wei, Shanghai, CN;

Tongruei Raymond Li, Shanghai, CN;

Jieqing Fan, Shanghai, CN;

Yanfang Pan, Shanghai, CN;

Huaixin Dang, Shanghai, CN;

Henri Lichenstein, Shanghai, CN;

Tian Xu, Shanghai, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61K 31/426 (2006.01); A61K 31/427 (2006.01); A61P 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/496 (2013.01); A61K 31/426 (2013.01); A61K 31/427 (2013.01); A61P 9/00 (2018.01);
Abstract

Provided herein are methods for inhibiting ALPK1 kinase activity using a compound of Formula I, and compositions and methods for therapy, for example in treating Kawasaki Disease.


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