The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2026

Filed:

Oct. 27, 2022
Applicant:

Praxis Precision Medicines, Inc., Boston, MA (US);

Inventors:

Kiran Reddy, Boston, MA (US);

Gabriel Maurice Belfort, Cambridge, MA (US);

Bernard Ravina, Newton, MA (US);

Marion Wittmann, Medford, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/445 (2006.01); A61K 9/20 (2006.01); A61P 25/08 (2006.01); A61P 25/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/445 (2013.01); A61K 9/2054 (2013.01); A61P 25/08 (2018.01); A61P 25/14 (2018.01);
Abstract

Described herein, in part, are methods useful for preventing and/or treating a disease or condition relating to aberrant function or activity of a T-type calcium channel, such as psychiatric disorders (e.g., mood disorder (e.g., major depressive disorder)), pain, tremor (e.g., essential tremor), seizures (e.g., absence seizures), epilepsy, or an epilepsy syndrome (e.g., juvenile myoclonic epilepsy). The present invention further comprises methods for modulating the function of a T-type calcium channel and methods of administering a titrated dosage of a T-type calcium channel antagonist.


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