The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 04, 2026
Filed:
Oct. 15, 2020
Applicants:
Amalive Limited, Cambridge, GB;
Mallinckrodt Enterprises Llc, Bedminster, NJ (US);
Inventors:
Xiaofeng Wang Rears, Boston, MA (US);
Jack Tseng, New York, NY (US);
Carmen Mak, Hampton, NJ (US);
Nagaraju Poola, Belle Mead, NJ (US);
Regis Vilchez, Chicago, IL (US);
Aniruddha Potnis, King of Prussia, PA (US);
Susan Vanmeter, Ashburn, VA (US);
Jan Stange, San Diego, CA (US);
Assignee:
Amalive Limited, Cambridge, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/198 (2006.01); A61P 1/16 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01);
U.S. Cl.
CPC ...
A61K 31/198 (2013.01); A61P 1/16 (2018.01); A61K 9/0019 (2013.01); A61K 9/08 (2013.01);
Abstract
Embodiments of the present disclosure relate to doses of ornithine phenylacetate for treating or ameliorating hyperammonemia and the methods of administrating the same in a patient with a chronic liver disease, for example, cirrhosis. In some embodiments, the patient also has hepatic encephalopathy as a complication of the liver disease.