The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 04, 2026
Filed:
Jun. 05, 2023
University of Maryland, College Park, College Park, MD (US);
Johns Hopkins University, Baltimore, MD (US);
Justin Stine, La Plata, MD (US);
Luke A. Beardslee, Atlanta, GA (US);
Reza Ghodssi, Potomac, MD (US);
Brian Holt, Huntingtown, MD (US);
Vivian Borbash, College Park, MD (US);
Hossein Abianeh, Gaithersburg, MD (US);
Michael Straker, Severn, MD (US);
Joshua Levy, Lanham, MD (US);
Pankaj J. Pasricha, Baltimore, MD (US);
University of Maryland, College Park, College Park, MD (US);
Abstract
The present disclosure describes various aspects of various devices, and methods of making and using the devices, for measuring bioimpedance of tissues within a patient's body, such as GI tract tissue. The devices entail using various implementations of capsules or other housings that allow for ingestion or other insertion into a body of the device, equipped with microfabricated sensors and embedded circuitry enabling wireless communication. Among other benefits, this approach addresses a gap in conventional GI tract monitoring devices and methods to non-invasively access the small intestine and directly measure the inflammatory state of intestinal tissue, including ischemia, edema, and mucosal abnormalities. The device integrates 1) bioimpedance measurements resulting from transmural contact of tetrapolar electrodes against intestinal tissue; 2) a packaging scheme for molding the electronics in a biocompatible polymer/resin and conformally wrapping the sensor on the surface of the capsule; and 3) a circuit configuration for signal acquisition and real-time wireless transmission to an external receiver.