The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2026
Filed:
May. 23, 2023
Geneheal Biotechnology Co., Ltd., Guangzhou, CN;
Wuguang Pan, Guangzhou, CN;
Wei Zhu, Guangzhou, CN;
Geneheal Biotechnology Co., Ltd., Guangzhou, CN;
Abstract
The present invention discloses application of compounds in the preparation of reagents for down-regulation of Runx2. The inventors have confirmed through computational studies and disease models that Fostamatinib, Regorafenib and melatonin can significantly down-regulate the expression of Runx2, and have a significant targeted therapeutic effect on cancers with abnormally high expression of Runx2, and are efficient reagents for reducing the expression of Runx2. Especially the Runx2 expression down-regulation reagent used in the laboratory.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile