The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2026

Filed:

Mar. 19, 2021
Applicants:

The General Hospital Corporation, Boston, MA (US);

Trustees of Tufts College, Boston, MA (US);

Inventors:

Derin Sevenler, Charlestown, MA (US);

Rebecca Sandlin, Melrose, MA (US);

Mehmet Toner, Charlestown, MA (US);

Giovanni Widmer, Newton, MA (US);

Saul Tzipori, Shrewsbury, MA (US);

Justyna Jaskiewicz, Boston, MA (US);

Assignees:

The General Hospital Corporation, Boston, MA (US);

Trustees Of Tufts College, Medford, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 1/04 (2006.01);
U.S. Cl.
CPC ...
C12N 1/04 (2013.01);
Abstract

Methods of bulk cryopreservation ofoocysts by vitrification using high aspect ratio cryopreservation devices are disclosed. Cryopreserved oocysts exhibit high viability, maintain infectivity in vitro, and are infectious to interferon-γ knockout mice. The course of the infection is comparable to that observed with unfrozen oocysts.


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