The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2026

Filed:

Sep. 21, 2021
Applicants:

Genfleet Therapeutics (Shanghai) Inc., Shanghai, CN;

Zhejiang Genfleet Therapeutics Co., Ltd., Zhejiang, CN;

Inventors:

Fusheng Zhou, Shanghai, CN;

Tao Jiang, Shanghai, CN;

Yingtao Liu, Shanghai, CN;

Chonglan Lin, Shanghai, CN;

Leitao Zhang, Shanghai, CN;

Zhubo Liu, Shanghai, CN;

Kai MA, Shanghai, CN;

Wan He, Shanghai, CN;

Xiaoming Xu, Shanghai, CN;

Lijian Feng, Shanghai, CN;

Xiaoling Lan, Shanghai, CN;

Qian Ding, Shanghai, CN;

Qiang Lv, Shanghai, CN;

Jiong Lan, Shanghai, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/22 (2006.01); A61K 31/4985 (2006.01); A61K 31/5386 (2006.01); A61P 35/00 (2006.01); C07D 471/14 (2006.01); C07D 471/22 (2006.01); C07D 491/22 (2006.01);
U.S. Cl.
CPC ...
C07D 498/22 (2013.01); A61K 31/4985 (2013.01); A61K 31/5386 (2013.01); A61P 35/00 (2018.01); C07D 471/14 (2013.01); C07D 471/22 (2013.01); C07D 491/22 (2013.01);
Abstract

Disclosed are an aroyl substituted tricyclic compound, a preparation method therefor and use thereof. Specifically, the aroyl substituted tricyclic compound of the present invention has a structure of formula (C), and has, as a BTK inhibitor, the advantages of high activity, good selectivity and low toxic and side effects.


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