The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2026

Filed:

Dec. 21, 2021
Applicant:

Hangzhou Healzen Therapeutics Co., Ltd., Hangzhou, CN;

Inventors:

Xinglu Zhou, Hangzhou, CN;

Xingguo Liu, Hangzhou, CN;

Miao Hu, Hangzhou, CN;

Jianrong Zhu, Hangzhou, CN;

Yizhe Wu, Hangzhou, CN;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01);
Abstract

The present disclosure discloses a crystal form of a casein kinase 1ε inhibitor and a preparation method and use of the crystal form. Specifically, the present disclosure relates to a crystal form of the compound (S)-2-(1-(4-amino-3-(2,3-difluoro-4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-5-chloro-3-phenylquinazoline-4(3H)one methanesulfonate and a preparation method and use of the crystal form. The crystal form of the casein kinase 1ε inhibitor compound of the present disclosure has good water solubility and oral absorption, and can be better used for the treatment of malignant tumors and autoimmune diseases that benefit from the inhibition of casein kinase 1ε activity.


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Zhou, Xinglu. (2026). Crystal form of casein kinase 1ϵ inhibitor and preparation method and use thereof (U.S. Patent No. 12692270). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12692270

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