The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2026

Filed:

Aug. 03, 2022
Applicant:

Abbisko Therapeutics Co., Ltd., Pudong New Area, CN;

Inventors:

Tao Feng, Pudong New Area, CN;

Baowei Zhao, Pudong New Area, CN;

Mingming Zhang, Pudong New Area, CN;

Shuqun Yang, Pudong New Area, CN;

Hongping Yu, Pudong New Area, CN;

Zhui Chen, Pudong New Area, CN;

Yaochang Xu, Pudong New Area, CN;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 31/506 (2006.01); A61P 35/00 (2006.01); C07D 403/04 (2006.01); C07D 403/14 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/506 (2013.01); A61P 35/00 (2018.01); C07D 403/04 (2013.01); C07D 403/14 (2013.01); C07D 519/00 (2013.01);
Abstract

A pyrimidine or pyridine derivative having a structure represented by formula (I), a preparation method therefor, a pharmaceutical composition containing same, a use thereof as an EGFR inhibitor, and a use thereof in the preparation of a drug for treating and/or preventing cancer, tumors, or metastatic diseases associated at least in part with EGFR exon 20 insertions, deletions, or other mutations, especially a use thereof in the preparation of a drug for treating and/or preventing hyperproliferative diseases and the induction of cell death disorders.


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