The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2026

Filed:

May. 19, 2025
Applicant:

2a Biosciences, Inc., New York, NY (US);

Inventor:

David E. Nichols, Chapel Hill, NC (US);

Assignee:

2A Biosciences, Inc., New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 217/60 (2006.01); A61K 31/137 (2006.01); A61P 25/00 (2006.01); C07C 215/52 (2006.01); C07C 217/48 (2006.01);
U.S. Cl.
CPC ...
C07C 217/60 (2013.01); A61K 31/137 (2013.01); A61P 25/00 (2018.01); C07C 215/52 (2013.01); C07C 217/48 (2013.01); C07C 2601/02 (2017.05);
Abstract

Novel compounds, such as phenethylamines having a 5-methoxymethyl or 5-hydroxymethyl substituent, are provided. In some aspects, pharmaceutical compositions comprising the compounds, methods of synthesizing the compounds, and methods of using such compounds, including their administration to subjects, are also provided. In some aspects, useful features of the compounds include neuromodulatory and/or anti-inflammatory activity, for example via activation of serotonin receptors. In some further aspects, the compounds are useful as therapeutic agents for treating medical conditions, such as psychiatric disorders and inflammatory conditions, including inflammation and inflammatory diseases and disorders.


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