The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2026
Filed:
Jul. 05, 2024
University of Maryland, Baltimore, Baltimore, MD (US);
Duke University, Durham, NC (US);
The Regents of the University of California, Oakland, CA (US);
Lei Ren, Clarksville, MD (US);
Zhuoran Jiang, Durham, NC (US);
Leshan Sun, Irvine, CA (US);
Liangzhong Xiang, Irvine, CA (US);
University of Maryland, Baltimore, MD (US);
Duke University, Durham, NC (US);
Regents of the University of California, Oakland, CA (US);
Abstract
Techniques for detecting real-time proton beam dose include retrieving conversion data for converting proton dose to acoustic pressure based on medical imagery. 3D medical imagery is retrieved of a first region of interest (ROI) inside a first subject. A real-time signal indicates ultrasound pressure at a 2D ultrasound array disposed outside and in contact with the first subject close to the first ROI. Real-time 3D dose delivered in the first ROI is determined by inputting the real-time signal into a dose detection module that includes a neural network. The neural network is trained on multiple instances of a training set. Each instance includes: simulated proton dose delivered to a similar ROI inside a second subject; simulated pressure generation from that simulated dose based on the conversion data and a similar 3D medical image; and simulated acoustic transmission from the similar ROI to a similar two-dimensional ultrasound transducer array similarly disposed.