The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2026

Filed:

Jun. 12, 2023
Applicants:

Centre for Eye and Vision Research Limited, Hong Kong, HK;

The Hong Kong Polytechnic University, Hong Kong, HK;

Inventors:

Chuen Lam, Hong Kong, HK;

Ying Hon Sze, Hong Kong, HK;

Yan Yin Tse, Hong Kong, HK;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4439 (2006.01); A61P 27/10 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4439 (2013.01); A61P 27/10 (2018.01);
Abstract

A pharmacologic treatment of refractive disorders, specifically myopia or hyperopia, by targeting the PPAR signaling pathway using a PPARγ agonist without any binding to PPARα. It is demonstrated that the PPARγ agonist modulates ocular growth through therapeutic intervention at the protein level of the PPAR signaling pathway. The effectiveness of the PPARγ agonist in regulating the PPAR signaling pathway and its associated proteins, as evidenced by experiments using a lens-induced myopia (LIM) animal model. More particularly, it is also demonstrated that the pharmacological reduction of myopic eye growth in terms of biometrics with dosage effect through the administration of the PPARγ agonist.


Find Patent Forward Citations

Lam, Chuen. (2026). Treating refractive disorders by targeting peroxisome proliferator-activated receptor (ppar) signaling pathway (U.S. Patent No. 12691106). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12691106

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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