The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2026
Filed:
Jun. 22, 2022
Jinan University, Guangzhou, CN;
Yubo Zhang, Guangzhou, CN;
Fei Xiao, Guangzhou, CN;
Guocai Wang, Guangzhou, CN;
Evandro Fei Fang, Shanghai, CN;
Junping Pan, Guangzhou, CN;
JINAN UNIVERSITY, Guangzhou, CN;
Abstract
Disclosed in the present invention is the use of Crassifolin A in promoting mitophagy and treating neurodegenerative diseases. According to the present invention, experiments show that the diterpene compound Crassifolin A can significantly increase mitophagy levels, promote the removal of damaged mitochondria, maintain homeostasis in cells, and has potential effects of treating neurodegenerative diseases and other related diseases; moreover, Crassifolin A is a small-molecule compound that can easily penetrate through the blood-brain barrier to reach the brain so as to play a role, can be extracted from a Thickleaf croton root medicinal material, has the advantages of abundant medicinal sources, easy availability, low drug toxicity and few side effects, and has a good application prospect in the treatment of neurodegenerative diseases.