The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 21, 2026

Filed:

Dec. 01, 2020
Applicant:

Neurocrine Biosciences, Inc., San Diego, CA (US);

Inventors:

Neil J. Ashweek, San Diego, CA (US);

John P. Williams, San Diego, CA (US);

Lev Alexander Zegelman, San Diego, CA (US);

Christina Marie Costa, San Diego, CA (US);

Scott Stirn, San Diego, CA (US);

Shawn Branum, San Diego, CA (US);

Jackie Le, San Diego, CA (US);

John Lloyd Tucker, San Diego, CA (US);

Brian M. Cochran, San Diego, CA (US);

David Kucera, San Diego, CA (US);

Donald Hettinger, San Diego, CA (US);

Max A. Mellmer, San Diego, CA (US);

Assignee:

Neurocrine Biosciences, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61P 5/00 (2006.01); C07D 231/54 (2006.01); C07D 233/20 (2006.01); C07D 487/04 (2006.01); G01N 33/74 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61P 5/00 (2018.01); C07D 231/54 (2013.01); C07D 233/20 (2013.01); G01N 33/74 (2013.01);
Abstract

Compounds are provided herein that antagonize corticotropin-releasing factor (CRF) receptors, in particular CRF receptor 1 (CRF), as well as related preparations, compositions and methods for treating diseases and/or disorders that would benefit from the same such as congenital adrenal hyperplasia (CAH).


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