The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 21, 2026
Filed:
Jul. 01, 2021
Guangzhou Healthquest Pharma Co., Ltd., Guangzhou, CN;
Ascentage Pharma (Suzhou) Co., Ltd., Suzhou, CN;
Ascentage Pharma Group Corp Limited, Hong Kong, CN;
Jianfeng Wen, Suzhou, CN;
Yanqiong Lin, Suzhou, CN;
Jianpeng Feng, Suzhou, CN;
Tianzhu Wu, Suzhou, CN;
Zhenzhong Shao, Suzhou, CN;
Weidong Li, Suzhou, CN;
Abstract
The invention discloses the crystal form, preparation method and application of an alkynyl compound, its salt and solvent compound. The invention specifically discloses 3-((1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazine-1-yl)methyl)-3-(trifluoromethyl)phenyl) benzamide crystal form I and 3-((1H-pyrazolo [3,4-b]pyridin-5-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazine-1-yl)methyl)-3-(trifluoromethyl)phenyl) benzamide fumarate crystal form II. The crystal form of the invention has good stability and has important value for drug optimization and development.