The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 21, 2026

Filed:

Sep. 29, 2022
Applicant:

Yuhan Corporation, Seoul, KR;

Inventors:

Eun-Kyung Kim, Seongnam-si, KR;

Cheol-Hee Lim, Suwon-si, KR;

Kang-Yo Lee, Seoul, KR;

Hyun-Ho Choi, Yongin-si, KR;

Assignee:

YUHAN CORPORATION, Seoul, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 235/14 (2006.01); A61K 31/4184 (2006.01); A61K 31/4192 (2006.01); A61K 31/4439 (2006.01); A61K 31/454 (2006.01); A61K 31/496 (2006.01); A61K 31/506 (2006.01); A61K 31/52 (2006.01); A61K 31/5377 (2006.01); A61K 31/675 (2006.01); C07D 249/18 (2006.01); C07D 403/10 (2006.01); C07D 403/12 (2006.01); C07D 487/04 (2006.01); C07F 9/6506 (2006.01); C07F 9/6518 (2006.01);
U.S. Cl.
CPC ...
C07D 235/14 (2013.01); A61K 31/4184 (2013.01); A61K 31/4192 (2013.01); A61K 31/4439 (2013.01); A61K 31/454 (2013.01); A61K 31/496 (2013.01); A61K 31/506 (2013.01); A61K 31/52 (2013.01); A61K 31/5377 (2013.01); A61K 31/675 (2013.01); C07D 249/18 (2013.01); C07D 403/10 (2013.01); C07D 403/12 (2013.01); C07D 487/04 (2013.01); C07F 9/65068 (2013.01); C07F 9/65188 (2013.01);
Abstract

Provided are a bicyclic fused ring, such as for example, benzo[d]imidazole, benzo[d][1,2,3]triazole, or 8-oxo-8,9-dihydro-7H-purine derivative, or pharmaceutically acceptable salt thereof, a process for the preparation thereof, a pharmaceutical composition comprising the same and a use thereof, wherein the bicyclic fused ring derivative or pharmaceutically acceptable salt thereof has an inhibitory activity against the lysyl oxidase family and can be usefully applied for preventing or treating various diseases associated with the lysyl oxidase family, such as idiopathic pulmonary fibrosis (IPF), non-alcoholic steatohepatitis (NASH), chronic kidney disease (CKD), or liver cirrhosis.


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