logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12685740 B1

PDFFull Text
Date of Patent:
Jul. 21, 2026

Filed:

Oct. 25, 2019

Compositions for the elimination of senescent cells

Applicants:

Universität Für Bodenkultur Wien, Vienna, AT;

Medizinische Universität Wien, Vienna, AT;

Inventors:

Ingo Lämmermann, Vienna, AT;

Johannes Grillari, Vienna, AT;

Vera Pils, Vienna, AT;

Florian Gruber, Vienna, AT;

Marie-Sophie Narzt, Vienna, AT;

Assignees:

UNIVERSITÄT FÜR BODENKULTUR WIEN, Vienna, AT;

MEDIZINISCHE UNIVERSITÄT WIEN, Vienna, AT;

Attorneys:

LOZA & LOZA, LLP

Michael F. Fedrick

Primary Examiner:

Bruck Kifle

Assistant Examiner:

Kevin S Martin

Int. Cl.
CPC ...
A61K 31/661 (2006.01); A61K 31/196 (2006.01); A61K 31/403 (2006.01); A61K 31/405 (2006.01); A61K 31/415 (2006.01); A61K 31/616 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); G01N 33/53 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
A61K 31/661 (2013.01); A61K 45/06 (2013.01); G01N 33/5308 (2013.01); G01N 33/56966 (2013.01); G01N 2500/10 (2013.01); G01N 2510/00 (2013.01); G01N 2800/7042 (2013.01);
Abstract

The invention relates to a composition comprising one or more inhibitors capable of inhibiting at least two of cyclooxygenase-1 (COX-1), cyclooxygenase-2 (COX-2) and lipoxygenase or a composition comprising one or more inhibitors capable of inhibiting an enzyme with arachidonate-Co A ligase activity, specifically long-chain-fatty-acid-Co A ligase (ACSL) 1, ACSL3, ACSL4, ACSL5, ACSL6, SLC27A2 or ACSBG2, or a combination thereof for use in selectively eliminating senescent cells. The invention further relates to an in vitro method of identifying senescent cells in a subject and to a method of identifying candidate compounds for the selective elimination of senescent cells.

Find Patent Forward Citations

Lämmermann, Ingo. (2026). Compositions for the elimination of senescent cells (U.S. Patent No. 12685740). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12685740

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…