The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 21, 2026
Filed:
Apr. 15, 2022
Eye and Ear Nose and Throat Hospital Affiliated to Fudan University, Shanghai, CN;
Xingtao Zhou, Shanghai, CN;
Jinhai Huang, Shanghai, CN;
Cuizhi Wang, Shanghai, CN;
Peijun Yao, Shanghai, CN;
Tian Han, Shanghai, CN;
Meiyan Li, Shanghai, CN;
Abstract
A method for detecting a penetration depth of riboflavin in a cornea includes acquiring an optical section of RGB colors and converting it into an image in a CIEL*a*b* color space, extracting a luminance component L* in the CIEL*a*b* color space, performing binarization and Blob analysis to obtain a non-corneal-region-free image; based on the non-corneal-region-free image and the luminance component L* image, extracting boundary points of anterior and posterior corneal surfaces and performing curve fitting, so as to obtain anterior and posterior corneal surface curves; performing image fusion on the anterior and posterior corneal surface curves into the CIEL*a*b* color space to obtain a cornea-only CIEL*a*b* color image; in the cornea-only CIEL*a*b* color image, locating a riboflavin-penetrating region and partitioning the riboflavin-penetrating region into riboflavin-penetrating sites, and performing curve fitting and noise reduction on the riboflavin-penetrating sites to obtain riboflavin the penetration depth and the anterior and posterior curves.