The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2026

Filed:

Oct. 16, 2019
Applicant:

Dh Technologies Development Pte. Ltd., Singapore, SG;

Inventors:

Jason Cournoyer, Jamaica Plain, MA (US);

Subhakar Dey, Lexington, MA (US);

Amy E. Trudel, Nashua, NH (US);

Subhasish Purkayastha, Framingham, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 30/86 (2006.01); G01N 33/68 (2006.01); G01N 33/74 (2006.01); H01J 49/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6848 (2013.01); G01N 33/74 (2013.01); G01N 30/8682 (2013.01); G01N 2458/15 (2013.01);
Abstract

Methods, compositions, kits, and apparatuses for MS-based quantification of a target analyte (e.g., a peptide, a hormone) in a sample are provided for increasing the productivity and/or throughput of samples by reducing the time and/or cost associated with conventional techniques for external instrument calibration that typically utilize a series of calibrators that are sequentially run through the same analytical process as a batch of samples. In various aspects, calibration mixtures are provided containing a known quantity of a plurality of calibrants for a target analyte of interest, with each calibrant being distinguishable in the calibration mixture by mass spectrometry such that a complete calibration curve can be generated from a single external calibration run.


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