The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2026

Filed:

Jun. 29, 2020
Applicant:

Zhonghongxin Investment Holdings (Shenzhen) Co., Ltd., Shenzhen, CN;

Inventors:

Jiajia Dong, Shanghai, CN;

Karl Barry Sharpless, Shanghai, CN;

Genyi Meng, Shanghai, CN;

Taijie Guo, Shanghai, CN;

Tiancheng MA, Shanghai, CN;

Assignee:

DEEPSYN. CO, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 413/14 (2006.01); C40B 30/00 (2006.01); C40B 30/06 (2006.01); C40B 50/04 (2006.01); C40B 60/08 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5011 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 413/14 (2013.01); C40B 30/06 (2013.01); C40B 50/04 (2013.01); C40B 60/08 (2013.01); B01J 2219/00315 (2013.01); B01J 2219/00736 (2013.01);
Abstract

The present invention provides a high throughput method for constructing and screening a compound library and a reaction device. Specifically, the method of the present invention comprises: (a) providing a reactor comprising n independent and addressable reaction chambers; (b) performing m independent synthesis reactions in said n reaction chambers, thereby constructing a compound library; and (c) performing activity tests in reaction chambers in which synthesis reactions are performed. In the present invention, the preparation and screening processes of a compound can be completed in the same reaction system. As the reactions of the present invention almost quantitatively generate products, the products can be directly used in enzymatic or even cytological activity test experiments without separation.


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