The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2026

Filed:

Jul. 26, 2018
Applicant:

Shenzhen Institutes of Advanced Technology, Shenzhen, CN;

Inventors:

Hairong Zheng, Shenzhen, CN;

Long Meng, Shenzhen, CN;

Congzhi Wang, Shenzhen, CN;

Xiufang Liu, Shenzhen, CN;

Yuchen Wang, Shenzhen, CN;

Wei Zhou, Shenzhen, CN;

Lili Niu, Shenzhen, CN;

Xiaowei Huang, Shenzhen, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/87 (2006.01); B01L 3/00 (2006.01); C12M 1/42 (2006.01);
U.S. Cl.
CPC ...
C12N 15/87 (2013.01); B01L 3/50273 (2013.01); B01L 2300/123 (2013.01); B01L 2400/0436 (2013.01); B01L 2400/0439 (2013.01);
Abstract

The gene transfection system includes an acoustothermal module and a signal generating module; the acoustothermal module includes a piezoelectric substrate, an acoustothermal chip arranged on the piezoelectric substrate and N sound-absorbing vessels arranged on the acoustothermal chip and used for cultivating recipient cells, and N is an integer greater than or equal to 1; the signal generating module is used to output basic frequency signals; the acoustothermal chip is used to convert the basic frequency signal to an acoustic wave signal, establish a temperature gradient field with the acoustic wave signal, and control the temperature of the recipient cell in the sound-absorbing vessels with the temperature gradient field, so that the pores are opened on the membranes of the recipient cell, and the nucleic acids or other substances can go into the cells through these pores.


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