The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2026
Filed:
Apr. 29, 2021
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);
Peter Kwong, Washington, DC (US);
Guillaume Stewart-Jones, Cambridge, MA (US);
Jason Gorman, New York, NY (US);
Li Ou, Potomac, MD (US);
Tongqing Zhou, Boyds, MD (US);
Baoshan Zhang, Bethesda, MD (US);
Wing-Pui Kong, Germantown, MD (US);
Yaroslav Tsybovsky, Brunswick, MD (US);
John Mascola, Rockville, MD (US);
Peter Collins, Kensington, MD (US);
Ursula Buchholz, Silver Spring, MD (US);
Abstract
Metapneumovirus (HMPV) F ectodomain trimers stabilized in a prefusion or postfusion conformation, nucleic acid molecules and vectors encoding these proteins, and methods of their use and production are disclosed. In several embodiments, the HMPV F ectodomain trimers and/or nucleic acid molecules can be used to generate an immune response to HMPV in a subject. In additional embodiments, the therapeutically effective amount of the HMPV F ectodomain trimers and/or nucleic acid molecules can be administered to a subject in a method of treating or preventing HMPV infection.