The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2026

Filed:

Oct. 05, 2020
Applicant:

Lab-on-a-bead Ab, Uppsala, SE;

Inventors:

Veronique Chotteau, Nacka, SE;

Kristofer Eriksson, Strängnäs, SE;

Sven Oscarsson, Stockholm, SE;

Nils Arnold Brechmann, Stockholm, SE;

Per-Olov Eriksson, Strängnäs, SE;

Assignee:

LAB-ON-A-BEAD AB, Uppsala, SE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/00 (2006.01); C07K 1/22 (2006.01); C12N 13/00 (2006.01); C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
C07K 1/22 (2013.01); C12M 29/10 (2013.01); C12M 47/10 (2013.01); C12N 13/00 (2013.01); C12P 21/02 (2013.01);
Abstract

There is provided a process for the separation of molecules from a suspension comprising cells at a concentration of at least 56×10cells/ml, comprising the steps of: a) providing magnetic particles having a specific interaction with said molecules to be separated, b) mixing the magnetic particles with the cell suspension containing the molecules, c) bringing the cell suspension in contact with a magnetic field provided by a magnetic separation device to collect the magnetic particles, d) decreasing or removing said magnetic field and collecting said magnetic particles carrying said molecules, and e) removing said molecules from said magnetic particles, to provide a concentrated fraction of said molecules, and/or provide partial or complete removal of impurities and cells from the fraction containing the molecules. Advantages include that the yield increases, the volume of the bioreactor and other equipment can be made smaller so that the process becomes more economical.


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