The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2026
Filed:
Oct. 02, 2023
Centessa Pharmaceuticals (Uk) Limited, Altrincham, GB;
John Andrew Christopher, Cambridge, GB;
Karl Gibson, Sandwich, GB;
Paul Humphries, Santa Clara, CA (US);
Gordon Saxty, Cambridge, GB;
Matthew Spendiff, Cambridge, GB;
Wojciech Zawodny, Cambridge, GB;
CENTESSA PHARMACEUTICALS (UK) LIMITED, Altrincham, GB;
Abstract
The present disclosure relates to compounds of Formula (I): and to their prodrugs, pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein are useful for modulating orexin-2 receptor activity and may be used in the treatment of disorders in which orexin-2 receptor activity is implicated, such as a neurodegenerative disorder, a symptom of a rare genetic disorder, a mental health disorder, a metabolic syndrome, osteoporosis, cardiac failure, coma, or a complication in emergence from anaesthesia.