The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2026

Filed:

Oct. 01, 2025
Applicant:

Cvrx, Inc., Minneapolis, MN (US);

Inventors:

Philip B. Adamson, Austin, TX (US);

Seth J. Wilks, Valparaiso, IN (US);

Paul Pignato, Jacksonville, FL (US);

Tucker Stuart, North Saint Paul, MN (US);

Bart Carey, Maplewood, MN (US);

Assignee:

CVRx, Inc., Minneapolis, MN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61N 1/36 (2006.01); A61N 1/02 (2006.01); A61N 1/372 (2006.01); G16H 40/67 (2018.01);
U.S. Cl.
CPC ...
A61N 1/36139 (2013.01); A61N 1/025 (2013.01); A61N 1/36114 (2013.01); A61N 1/36132 (2013.01); A61N 1/36142 (2013.01); A61N 1/37282 (2013.01); G16H 40/67 (2018.01);
Abstract

Systems and methods are provided for delivering closed-loop or partially closed-loop baroreflex activation therapy (BAT) to treat conditions associated with autonomic dysfunction. A pulse generator delivers stimulation while physiological data, such as ECG, heart rate variability, bioimpedance, and physical activity levels, is collected from one or more sensors. The data is analyzed to assess autonomic nervous system activity, and stimulation parameters are dynamically adjusted in response. In some embodiments, adjustments are made on a beat-to-beat basis using ECG input. Artificial intelligence algorithms may be used to predict patient-specific responses, optimize therapy, and evaluate effectiveness. The method may further include integrating patient-reported symptoms, wirelessly transmitting data, or adjusting stimulation duty cycle based on time of day. The system may further incorporate patient-reported symptoms, a clinician dashboard for remote monitoring, and a multi-channel lead. Stimulation may be delivered non-invasively or via an implantable device.


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