The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2026
Filed:
Nov. 10, 2022
Shanghai Ruizhikang Medical Technology Co., Ltd., Shanghai, CN;
Xiaohong Chen, Shanghai, CN;
Yubo Liu, Shanghai, CN;
Honglei Zhou, Shanghai, CN;
Wei Li, Shanghai, CN;
Fengcang MA, Shanghai, CN;
Shaoli Fu, Shanghai, CN;
Guosen Shao, Shanghai, CN;
Haochen Wu, Shanghai, CN;
SHANGHAI RUIZHIKANG MEDICAL TECHNOLOGY CO., LTD., Shanghai, CN;
Abstract
The present disclosure provides a fiber membrane and a preparation method and use thereof, and belongs to the field of biological materials. The fiber membrane includes a fiber with a core-shell structure, where a core of the fiber includes simvastatin and a first spinnable polymer, and a shell of the fiber includes hydroxyapatite and a second spinnable polymer. In the fiber, a release of the simvastatin mainly depends on a rate of water invasion. After water invades the fiber, the simvastatin in the fiber leaves the fiber with the diffusion of water. In the present disclosure, a barrier function of the shell prevents moisture from entering the core. Therefore, the simvastatin in the core cannot leave the fiber with the diffusion of water molecules in an early stage, and a release rate of drugs is slowed down in the early stage, thereby controlling sustained release of the drugs.