The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2026
Filed:
Jun. 22, 2021
Applicant:
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Inventors:
Nathanael S. Gray, Stanford, CA (US);
Baishan Jiang, Watertown, MA (US);
David Weinstock, Jamaica Plain, MA (US);
Wenchao Wu, Brookline, MA (US);
Assignee:
DANA-FARBER CANCER INSTITUTE, INC., Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/54 (2017.01); A61K 39/00 (2006.01); A61K 40/31 (2025.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/545 (2017.08); A61K 39/00 (2013.01); A61K 40/31 (2025.01); A61P 35/00 (2018.01);
Abstract
Disclosed are bispecific compounds (degraders) that target ITK or a zinc finger (ZnF) protein for degradation. Also disclosed are pharmaceutical compositions containing the degraders and methods of using the compounds to treat diseases and disorders characterized or mediated by ITK or ZnF protein activity.