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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12678486 B1

PDFFull Text
Date of Patent:
Jul. 14, 2026

Filed:

Mar. 25, 2021

Cell immunotherapy for the treatment of cancer

Applicant:

Board of Regents, the University of Texas System, Austin, TX (US);

Inventors:

Katy Rezvani, Houston, TX (US);

Mayra Shanley, Houston, TX (US);

David Marin Costa, Houston, TX (US);

Hila Shaim, Houston, TX (US);

Elizabeth Shpall, Houston, TX (US);

Assignee:

BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US);

Attorney:

Norton Rose Fulbright US LLP

Primary Examiner:

Prema M Mertz

Int. Cl.
CPC ...
A61K 38/20 (2006.01); A61K 40/15 (2025.01); A61K 40/42 (2025.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); C07K 14/54 (2006.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
A61K 38/208 (2013.01); A61K 38/20 (2013.01); A61K 40/15 (2025.01); A61K 40/4234 (2025.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07K 14/54 (2013.01); C07K 14/5434 (2013.01); C12N 5/0646 (2013.01); A61K 2239/31 (2023.05); A61K 2239/38 (2023.05); A61K 2239/47 (2023.05);
Abstract

Embodiments of the disclosure encompass compositions comprising immune effector cells, such as natural killer (NK) cells, where the cells comprise one or more exogenously provided interleukins (IL), and wherein the cell optionally comprises one or more engineered receptors. In specific embodiments, the IL is not IL-15, and is IL-12, IL-21, or both. The NK cells may be utilized for treatment of cancer of any kind, including at least glioblastoma.

Find Patent Forward Citations

Rezvani, Katy. (2026). Cell immunotherapy for the treatment of cancer (U.S. Patent No. 12678486). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12678486

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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