The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2026

Filed:

Jun. 08, 2022
Applicants:

The United States Government As Represented BY the Department of Veterans Affairs, Washington, DC (US);

The Board of Trustees of the University of Illinois, Urbana, IL (US);

Inventors:

Hee-Jeong Im Sampen, Chicago, IL (US);

Ying Liu, Chicago, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 9/00 (2006.01); A61K 31/506 (2006.01); A61K 35/28 (2015.01); A61K 47/26 (2006.01); A61P 19/02 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5153 (2013.01); A61K 9/0019 (2013.01); A61K 31/506 (2013.01); A61K 35/28 (2013.01); A61K 47/26 (2013.01); A61P 19/02 (2018.01);
Abstract

Disclosed herein are nanoparticles comprising Pazopanib or a derivative thereof encapsulated by the copolymer poly (lactic-co-glycolic acid) (PLGA). Also disclosed herein are methods for treating osteoarthritis, inhibiting or preventing cartilage degeneration, and reducing or inhibiting pain-associated depression in subjects with joint pain with nanoparticles comprising Pazopanib or a derivative thereof.


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