The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2026

Filed:

Oct. 06, 2023
Applicants:

Ventana Medical Systems, Inc., Tucson, AZ (US);

Genentech, Inc., South San Francisco, CA (US);

Inventors:

Xingwei Wang, Sunnyvale, CA (US);

Auranuch Lorsakul, Santa Clara, CA (US);

Zuo Zhao, Palo Alto, CA (US);

Yao Nie, Sunnyvale, CA (US);

Hartmut Koeppen, San Mateo, CA (US);

Hauke Kolster, Fresno, CA (US);

Kandavel Shanmugam, Oro Valley, AZ (US);

Assignees:

Ventana Medical Systems, Inc., Tucson, AZ (US);

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06T 7/00 (2017.01); G16H 30/40 (2018.01);
U.S. Cl.
CPC ...
G06T 7/0012 (2013.01); G16H 30/40 (2018.01); G06T 2207/20081 (2013.01); G06T 2207/20084 (2013.01);
Abstract

The present disclosure relates to techniques for obtaining a synthetic immunohistochemistry (IHC) image from a histochemically stained image. Particularly, aspects of the present disclosure are directed to accessing an input image that depicts a tissue section that has been stained with at least one histochemical stain; generating a synthetic image by processing the input image using a trained generator network; and outputting the synthetic image. The synthetic image depicts a tissue section that has been stained with at least one IHC stain that targets a first antigen, and techniques may also include receiving an input that is based on a level of expression of a first antigen from the synthetic image and/or generating, from the synthetic image, a value that is based on a level of expression of the first antigen.


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