The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2026
Filed:
Oct. 16, 2023
Applicant:
Kyoto University, Kyoto, JP;
Inventors:
Assignee:
KYOTO UNIVERSITY, Kyoto, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); C12N 5/074 (2010.01); C12N 15/09 (2006.01); A61K 35/22 (2015.01); A61L 27/38 (2006.01); A61P 13/12 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0687 (2013.01); C12N 5/0696 (2013.01); C12N 2501/115 (2013.01); C12N 2501/119 (2013.01); C12N 2501/155 (2013.01); C12N 2501/998 (2013.01); C12N 2533/52 (2013.01);
Abstract
A method of producing a mesodermal-lineage primitive streak cell includes a first step of culturing pluripotent stem cells in a medium containing FGF2, BMP (bone morphogenetic protein) 4, a GSK-3β inhibitor, and retinoic acid or a derivative thereof and a second step of culturing cells obtained in the first step in a medium containing FGF2, a GSK-3β inhibitor, and BMP7.