The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2026

Filed:

Apr. 09, 2018
Applicant:

Nkmax Co., Ltd., Seongnam-Si, KR;

Inventors:

Kyung Mi Lee, Seoul, KR;

Seon Ah Lim, Seoul, KR;

Cassian Yee, Seoul, KR;

Assignee:

NKMAX Co., Ltd., Seongnam-Si, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0783 (2010.01); A61K 35/17 (2025.01); A61K 40/15 (2025.01); A61K 40/46 (2025.01);
U.S. Cl.
CPC ...
C12N 5/0646 (2013.01); A61K 40/15 (2025.01); A61K 40/46 (2025.01); C12N 2501/2302 (2013.01); C12N 2502/1114 (2013.01); C12N 2502/30 (2013.01);
Abstract

The present invention relates to a method for inducing and expanding natural killer cells derived from peripheral blood mononuclear cells, which comprises co-culturing, as feeder cells, irradiated Jurkat cells and irradiated Epstein-Barr virus transformed lymphocyte continuous line (EBV-LCL) cells in the presence of cytokines, along with peripheral blood mononuclear cells. According to the present invention, a large quantity of natural killer cells can be induced and proliferated from a small quantity of peripheral blood mononuclear cells even without the use of high-cost equipment or various kinds of expensive cytokines, thereby making it possible to significantly improve the efficiency and efficacy of the prevention and treatment of cancer using the natural killer cells.


Find Patent Forward Citations

Lee, Kyung. (2026). Method for the induction and expansion of natural killer cells derived from peripheral blood mononuclear cells (U.S. Patent No. 12674138). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12674138

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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