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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12673947 B1

PDFFull Text
Date of Patent:
Jul. 07, 2026

Filed:

Jul. 22, 2021

Pyrido-pyrazinyl compounds for treating acute myeloid leukemia

Applicant:

Cytosinlab Therapeutics Co., Ltd., Shanghai, CN;

Inventors:

Haiping Wu, Shanghai, CN;

Meng Wang, Shanghai, CN;

Yuan Mi, Shanghai, CN;

Xingnian Fu, Shanghai, CN;

Hui Shi, Shanghai, CN;

Jiannan Guo, Shanghai, CN;

Assignee:

Cytosinlab Therapeutics Co. Ltd., Shanghai, CN;

Attorney:

ICE MILLER LLP

Primary Examiner:

Jennifer A Berrios

Assistant Examiner:

Sophia undefined Reilly

Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 487/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 487/04 (2013.01); C07D 519/00 (2013.01);
Abstract

The present invention provides compounds having kinase inhibitory activity. Specifically, the present invention provides compounds having a structure represented by the following formula (II). The compound of the present invention has good inhibitory activity for a variety of kinases (e.g. ALK, AXL, EGFR, and FLT3), and therefore can be used for preparing a pharmaceutical composition for treating kinase activity-related diseases (e.g. acute myeloid leukemia, etc.).

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Wu, Haiping. (2026). Pyrido-pyrazinyl compounds for treating acute myeloid leukemia (U.S. Patent No. 12673947). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12673947

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