The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2026
Filed:
Nov. 12, 2020
Yuhan Corporation, Seoul, KR;
Green Cross Corporation, Yongin-si, KR;
Dong-Hoon Kim, Suwon-si, KR;
Jae-Eun Joo, Yongin-si, KR;
Eui-Chul Lee, Yongin-si, KR;
Tae-Dong Han, Yongin-si, KR;
Seung-Yub Shin, Osan-si, KR;
Sool-Ki Kwon, Yongin-si, KR;
YUHAN CORPORATION, Seoul, KR;
GREEN CROSS CORPORATION, Yongin-si, KR;
Abstract
Provided are a compound of Formula 1 having a chromane, isochromane, thiochromane, or tetrahydroquinoline moiety or pharmaceutically acceptable salt thereof, a process for the preparation thereof, a pharmaceutical composition comprising the same and a use thereof, wherein the compound having a chromane, isochromane, thiochromane, or tetrahydroquinoline moiety or pharmaceutically acceptable salt thereof has an inhibitory activity against glucosylceramide synthase (GCS), and therefore can be usefully applied for preventing or treating various diseases associated with GCS, such as Gaucher disease, Fabry disease, Tay-Sachs disease, Parkinson's disease, etc.: