The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2026
Filed:
Jul. 29, 2021
Applicant:
Exelixis, Inc., Alameda, CA (US);
Inventors:
Gisela Schwab, Hayward, CA (US);
Christian Scheffold, Palo Alto, CA (US);
Colin Chong, Fremont, CA (US);
Ssucheng Jeff Hsu, Pinole, CA (US);
Peter Lamb, Oakland, CA (US);
Peiwen Yu, San Mateo, CA (US);
Assignee:
Exelixis, Inc., Alameda, CA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/47 (2006.01); A61K 38/20 (2006.01); A61K 45/06 (2006.01); A61P 35/04 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 31/47 (2013.01); A61K 38/2013 (2013.01); A61K 45/06 (2013.01); A61P 35/04 (2018.01); C07K 16/2818 (2013.01); C07K 16/2827 (2013.01); C07B 2200/13 (2013.01);
Abstract
The present invention relates to combinations comprising a checkpoint inhibitor and a c-Met inhibitor, Compound 1. The invention also relates to crystalline forms of the free base of Compound 1, as well as crystalline forms of salts of Compound 1, in combination with a checkpoint inhibitor. The invention further relates to methods of treating cancer by administering Compound 1 as a single agent or a combination described herein.