The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2026

Filed:

Jun. 06, 2019
Applicant:

Minoryx Therapeutics S.l., Mataró Barcelona, ES;

Inventors:

Marc Martinell Pedemonte, Mataró Barcelona, ES;

Maria Pilar Pizcueta Lalanza, Mataró Barcelona, ES;

Guillem Pina Laguna, Mataró Barcelona, ES;

Uwe Meya, Mataró Barcelona, ES;

Alan Bye, Horsham, GB;

Assignee:

MINORYX THERAPEUTICS S.L., Mataró Barcelona, ES;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4439 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4439 (2013.01); A61K 9/0053 (2013.01);
Abstract

The present disclosure provides methods of treating a disease or disorder in a patient comprising administering 5-[[4-[2-[5-(1-hydroxyethyl)pyridin-2-yl]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione ('Compound (1)'), or a pharmaceutically acceptable salt thereof, to the patient, wherein the patient achieves a threshold steady-state plasma concentration of Compound (1). The present disclosure also provides methods of administering a therapeutically effective amount of Compound (1), or a pharmaceutically acceptable salt thereof, to a patient. Compound (1) is a PPAR-γ agonist that is used to treat a variety of diseases and disorders including, but not limited to, nonalcoholic steatohepatitis and central nervous system diseases, e.g., X-linked adrenoleukodystrophy, Friedreich's Ataxia.


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