The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 30, 2026

Filed:

Apr. 15, 2021
Applicants:

Japan As Represented BY Director General of National Institute of Health Sciences, Kanagawa, JP;

Tosoh Corporation, Yamaguchi, JP;

Inventors:

Yoshiro Saito, Kanagawa, JP;

Ryosuke Nakamura, Kanagawa, JP;

Noriaki Arakawa, Kanagawa, JP;

Yasuo Ohno, Kanagawa, JP;

Takashi Izumi, Kanagawa, JP;

Motonobu Sato, Ibaraki, JP;

Takayoshi Nishiya, Tokyo, JP;

Michiko Aihara, Kanagawa, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); G01N 33/94 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); G01N 33/94 (2013.01); G01N 2800/50 (2013.01); G01N 2800/56 (2013.01);
Abstract

Biomarkers for diagnosing the disease activity, disease severity or disease type of severe cutaneous adverse drug reactions (SCARs) such as drug-induced hypersensitivity syndrome and Stevens-Johnson syndrome/toxic epidermal necrolysis are provided. Also provided is a method of testing SCARs, comprising measuring the expression of at least one protein selected from the group consisting of stratifin, TNF receptor superfamily member 8 (CD30/TNFRSF8), interleukin-1 receptor antagonist (IL-1Ra), and TNF receptor superfamily member 6B (DcR3/TNFRSF6B) in a sample derived from a subject.


Find Patent Forward Citations

Saito, Yoshiro. (2026). Protein diagnostic biomarker for severe cutaneous drug adverse reactions (U.S. Patent No. 12669512). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12669512

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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