The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 30, 2026

Filed:

Jul. 14, 2023
Applicant:

Melio Healthcare Limited, London, GB;

Inventors:

Adam Laing, London, GB;

Thomas Hayday, London, GB;

Jennie Yang, London, GB;

Jeremy Mason, Cambridge, GB;

Eduardo Alves, London, GB;

Per Ullberg, Knivsta, SE;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G16B 20/00 (2019.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56972 (2013.01); G16B 20/00 (2019.02);
Abstract

Method and systems for generating an immune profile for a subject are described. In some instances, the methods comprise contacting at least a first aliquot of a sample from the subject with at least a first immunophenotyping panel to fluorescently-label cells contained within the sample; processing the fluorescently-labeled cells using a full spectrum flow cytometer to generate fluorescence intensity data, or data derived therefrom, for fluorescently-labeled cells from the sample; providing at least a subset of the fluorescence intensity data, or data derived therefrom, for the fluorescently-labeled cells as input to an ensemble machine learning model configured to process the data and classify individual cells as belonging to one of a plurality of distinct immune cell sub-populations; and outputting a total cell count or cell frequency for each of the plurality of distinct immune cell sub-populations in the sample as part of an immune profile for the subject.


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