The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 30, 2026
Filed:
Nov. 13, 2020
Monash University, Clayton, AU;
National University of Singapore, Singapore, SG;
Nantes Université, Nantes, FR;
Jose Polo, Clayton, AU;
Xiaodong Liu, Clayton, AU;
Kathryn Davidson, Clayton, AU;
Owen Rackham, Singapore, SG;
John F. Ouyang, Singapore, SG;
Laurent David, Nantes, FR;
Gael Castel, Nantes, FR;
Monash University, Clayton, AU;
National University of Singapore, Singapore, SG;
NANTES UNIVERSITE, Nantes, FR;
Abstract
The present invention provides a method for reprogramming a human somatic cell to a cell exhibiting at least one characteristic of a trophoblast stem cell (TSC), the method comprising the following steps in order: a) increasing the protein expression of one or more factors in the somatic cell, wherein the factors are for reprogramming the somatic cell towards a pluripotent state; b) culturing the cell for a sufficient time and under conditions to allow the reprogramming of the cell towards a pluripotent state; c) contacting the cell with a culture medium suitable for sustaining trophoblast stem cells (TSC); and d) culturing the cell in the TSC medium for a sufficient time and under conditions to allow the cell to exhibit at least one characteristic of a TSC, thereby reprogramming the somatic cell to a cell exhibiting at least one characteristic of a TSC.