The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 30, 2026

Filed:

Jul. 24, 2020
Applicant:

North Carolina State University, Raleigh, NC (US);

Inventors:

Jonathan S. Lindsey, Raleigh, NC (US);

Hikaru Fujita, Ishikawa, JP;

Nobuyuki Matsumoto, Raleigh, NC (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08B 33/00 (2006.01); A61K 51/06 (2006.01);
U.S. Cl.
CPC ...
C08B 33/00 (2013.01); A61K 51/065 (2013.01);
Abstract

Compounds comprising a cross-linking moiety and a protecting group are described herein along with their methods of use. The cross-linking moiety may comprise an indoxyl and the protecting group may comprise a sugar (e.g., a glucuronide or glucoside), phosphoester, or sulfoester group. The cross-linking moiety and protecting group may be attached to each other via an oxygen atom, sulfur atom, or linker. In some embodiments, the linker attaching the cross-linking moiety and protecting group is a self-immolative linker. A compound of the present invention may cross-link under physiological conditions and/or in vivo.


Find Patent Forward Citations

Lindsey, Jonathan. (2026). Cross-linking compounds and methods of use thereof (U.S. Patent No. 12668646). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12668646

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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