The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 30, 2026

Filed:

Aug. 10, 2021
Applicant:

Dana-farber Cancer Institute, Inc., Boston, MA (US);

Inventors:

Sara Buhrlage, Somerville, MA (US);

Anthony Varca, Brookline, MA (US);

Bin Hu, Natick, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 233/65 (2006.01); C07C 311/46 (2006.01); C07C 317/40 (2006.01); C07D 233/61 (2006.01); C07D 295/108 (2006.01); C07D 295/135 (2006.01); C07D 295/26 (2006.01);
U.S. Cl.
CPC ...
C07C 311/46 (2013.01); C07C 233/65 (2013.01); C07C 317/40 (2013.01); C07D 233/61 (2013.01); C07D 295/108 (2013.01); C07D 295/135 (2013.01); C07D 295/26 (2013.01);
Abstract

The present disclosure relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof and pharmaceutical composition comprising the compound of formula (I). The present composition also relates to methods treating a disease or disorder associated with ubiquitin-specific protease 28 (USP28), methods of treating cancer, and methods of inhibiting USP28.


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