The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 30, 2026

Filed:

Oct. 07, 2021
Applicant:

Academia Sinica, Taipei, TW;

Inventors:

Shang-Cheng Hung, Taipei City, TW;

Chi-Huey Wong, Taipei City, TW;

Veeranjaneyulu Gannedi, Taipei, TW;

Bharath Kumar Villuri, Taipei, TW;

Nimmakayala Sivakumar Reddy, Taipei, TW;

Chiao-Chu Ku, Taipei City, TW;

Assignee:

Academia Sinica, Taipei, TW;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01J 31/02 (2006.01); C07H 1/02 (2006.01); C07H 7/06 (2006.01);
U.S. Cl.
CPC ...
B01J 31/0245 (2013.01); C07H 1/02 (2013.01); C07H 7/06 (2013.01);
Abstract

Disclosed herein are novel catalysts for producing remdesivir in one-pot manner, in which a diastereomerically enriched form of an intermediate, which following acidic hydrolysis would give rise to the desired remdesivir, was produced with the aid of the disclosed novel catalysts. Also disclosed herein is an improved process for the preparation of remdesivir without the need to separate one of the enantiomers while minimizing the formation of undesired isomers, thus offers economic advantages for operation on a commercial scale.


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