The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 30, 2026

Filed:

Feb. 01, 2021
Applicants:

Five Eleven Pharma, Inc, Philadelphia, PA (US);

Biomolecular Probes Biotechnology (Beijing) Co., Ltd, Beijing, CN;

Inventors:

Hank F Kung, Philadelphia, PA (US);

Zhihao Zha, Beijing, CN;

Karl Ploessl, Philadelphia, PA (US);

Seok Rye Choi, Philadelphia, PA (US);

David Alexoff, Philadelphia, PA (US);

Assignees:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/04 (2006.01);
U.S. Cl.
CPC ...
A61K 51/0455 (2013.01); A61K 2123/00 (2013.01);
Abstract

A radioactively labeled ligand for a fibroblast activation protein-alpha imaging agent and a preparation method therefor are provided. The radioactively labeled ligand for the fibroblast activation protein-alpha imaging agent has structural formal (I). The compound has a goodGa labeling property, a high stability and a good affinity for FAP tumors. The radioactively labeled ligand forGa-labeled FAPi can be used as a tumor positron imaging agent.


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