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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12667580 B1

PDFFull Text
Date of Patent:
Jun. 30, 2026

Filed:

Jul. 20, 2022

Retinoic acid precursor and anticancer drug composition comprising same

Applicant:

Industrial Cooperation Foundation Jeonbuk National University, Jeonju-si, KR;

Inventors:

Dong Won Lee, Jeonju-si, KR;

Eun Kyeong Jung, Suncheon-si, KR;

Assignee:

INDUSTRIAL COOPERATION FOUNDATION JEONBUK NATIONAL UNIVERSITY, Jeonju-si, KR;

Attorneys:

Bridgeway IP Law Group, PLLC

Jihun Kim

Primary Examiner:

Sin J Lee

Int. Cl.
CPC ...
A61K 31/69 (2006.01); A61K 9/14 (2006.01); A61K 9/51 (2006.01); A61K 31/203 (2006.01); A61K 31/222 (2006.01); A61K 31/232 (2006.01); A61P 35/00 (2006.01); C07F 5/02 (2006.01);
U.S. Cl.
CPC ...
A61K 31/69 (2013.01); A61K 9/14 (2013.01); A61K 9/146 (2013.01); A61K 9/5146 (2013.01); A61K 31/203 (2013.01); A61K 31/222 (2013.01); A61K 31/232 (2013.01); A61P 35/00 (2018.01); C07F 5/02 (2013.01); C07F 5/025 (2013.01); C07F 5/027 (2013.01);
Abstract

A retinoic acid prodrug to which a boron functional group having a structure represented by chemical formula 1 is bound is described. The retinoic acid prodrug self-assembles to form nanoparticles. Therefore, an anticancer drug composition comprises the same as an active ingredient. According to the retinoic acid prodrug, targeted therapy of tumor cells is possible through the synergistic anticancer effect of retinoic acid and the boron functional group and the surface modification of particles. In particular, the retinoic acid prodrug enables a drug loading of 100 wt %, and thus can provide an effective anticancer drug.

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Lee, Dong. (2026). Retinoic acid precursor and anticancer drug composition comprising same (U.S. Patent No. 12667580). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12667580

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