The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 30, 2026

Filed:

Feb. 09, 2021
Applicants:

Genfleet Therapeutics (Shanghai) Inc., Shanghai, CN;

Zhejiang Genfleet Therapeutics Co., Ltd., Zhejiang, CN;

Inventors:

Fusheng Zhou, Shanghai, CN;

Xiaoming Xu, Shanghai, CN;

Leitao Zhang, Shanghai, CN;

Xin Li, Shanghai, CN;

Lili Tang, Shanghai, CN;

Jiong Lan, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4375 (2006.01); A61K 31/4184 (2006.01); A61K 31/4188 (2006.01); A61K 31/423 (2006.01); A61K 31/5025 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4375 (2013.01); A61K 31/4184 (2013.01); A61K 31/4188 (2013.01); A61K 31/423 (2013.01); A61K 31/5025 (2013.01);
Abstract

Provided are a dihydronaphthyridinone compound as shown in formula (I), which compound has a selective inhibitory effect on RIPK1, and a pharmaceutically acceptable salt, a stereoisomer, a solvate or a prodrug thereof. In addition, provided are a pharmaceutical composition containing the compound, and the use thereof in the preparation of a drug for treating RIPK1-related diseases or conditions.


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