logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12663414 B1

PDFFull Text
Date of Patent:
Jun. 23, 2026

Filed:

Jul. 29, 2022

Platform for co-culture imaging to characterize in vitro efficacy of heterotypic effector cellular therapies in cancer

Applicant:

Tempus Ai, Inc., Chicago, IL (US);

Inventors:

Chi-Sing Ho, Redwood City, CA (US);

Madhavi Kannan, Bloomington, IL (US);

Sonal Khare, Chicago, IL (US);

Brian Larsen, Chicago, IL (US);

Brandon Mapes, Chicago, IL (US);

Ameen Salahudeen, Oak Park, IL (US);

Jagadish Venkataraman, Menlo Park, CA (US);

Assignee:

TEMPUS AI, INC., Chicago, IL (US);

Attorney:

MARSHALL, GERSTEIN & BORUN LLP

Primary Examiner:

Stephen R Koziol

Assistant Examiner:

Joshua undefined Chen

Int. Cl.
CPC ...
G01N 33/50 (2006.01); G01N 21/64 (2006.01); G06T 3/06 (2024.01); G06T 7/00 (2017.01); G06T 7/11 (2017.01); G06V 10/774 (2022.01); G06V 20/69 (2022.01); G16H 15/00 (2018.01); G16H 30/40 (2018.01);
U.S. Cl.
CPC ...
G01N 33/5082 (2013.01); G01N 21/6428 (2013.01); G01N 21/6456 (2013.01); G01N 33/5011 (2013.01); G06T 3/06 (2024.01); G06T 7/0016 (2013.01); G06T 7/11 (2017.01); G06V 10/774 (2022.01); G06V 20/695 (2022.01); G06V 20/698 (2022.01); G16H 15/00 (2018.01); G16H 30/40 (2018.01); G01N 2021/6439 (2013.01); G06T 2200/04 (2013.01); G06T 2207/10064 (2013.01); G06T 2207/20081 (2013.01); G06T 2207/30024 (2013.01); G06T 2207/30072 (2013.01);
Abstract

A method for characterizing cancer organoid response to an immune cell based therapy, includes providing a panel of different combinations of cancer organoid cells and immune cells to culturing wells and culturing the different combination under conditions that support organoid growth. Brightfield and corresponding fluorescence images of the culturing wells are captured and provided to one or more trained machine learning algorithms that identify and distinguish cancer organoid cells from immune cells and characterize cancer organoid morphology changes caused by an immune cell based therapies, from which an analytical report including a characterization of cancer organoid cell death caused by the immune cell based therapy is provided.

Find Patent Forward Citations

Ho, Chi-Sing. (2026). Platform for co-culture imaging to characterize in vitro efficacy of heterotypic effector cellular therapies in cancer (U.S. Patent No. 12663414). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12663414

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…