The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2026

Filed:

Jan. 23, 2025
Applicants:

The Trustees of Columbia University IN the City of New York, New York, NY (US);

The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);

Revolution Medicines, Inc., Redwood City, CA (US);

Inventors:

Kenneth Paul Olive, New York, NY (US);

Urszula Wasko, New York, NY (US);

Channing Der, Chapel Hill, NC (US);

Mallika Singh, Redwood City, CA (US);

Jingjing Jiang, Redwood City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/156 (2013.01);
Abstract

Methods of treating a tumor in a subject comprising administering to the subject an amount of a RASinhibitor and an amount of a TEAD inhibitor, effective to treat a tumor, and methods of treating a tumor resistant to a RASinhibitor therapy comprising administering to a tumor so-identified an amount of a RASinhibitor and an amount of a TEAD inhibitor, effective to treat a tumor resistant to a RASinhibitor therapy.


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