The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2026

Filed:

Aug. 07, 2019
Applicant:

Sumitomo Pharma Co., Ltd., Osaka, JP;

Inventors:

Seiji Kamioka, Toyonaka, JP;

Naoaki Shimada, Takatsuki, JP;

Hitoshi Ban, Nishinomiya, JP;

Kazuto Yamazaki, Ikoma, JP;

Akihiko Arakawa, Odawara, JP;

Wataru Hirose, Suita, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 519/00 (2006.01); A61P 35/02 (2006.01); C07D 453/06 (2006.01); C07D 513/04 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01); A61P 35/02 (2018.01); C07D 453/06 (2013.01); C07D 513/04 (2013.01);
Abstract

The present invention relates to the compound of formula (1a) wherein a-d and p are 1 or 2, R-Rare hydrogen atom or the like, and Ris —CFor the like, or a pharmaceutically acceptable salt thereof, which has an anticancer effect by inhibiting the binding between a MLL fusion protein that is fused with AF4, AF9, or the like, which is a representative fusion partner gene causing MLL leukemia, and menin.


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