The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2026

Filed:

Dec. 01, 2023
Applicant:

Baebies, Inc., Durham, NC (US);

Inventors:

Daniel Wu, Durham, NC (US);

Rainer Ng, Durham, NC (US);

Greg Smith, Durham, NC (US);

Vijay Srinivasan, Durham, NC (US);

Vamsee Pamula, Durham, NC (US);

Assignee:

Baebies, Inc., Durham, NC (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); B01L 3/00 (2006.01); B01L 7/00 (2006.01);
U.S. Cl.
CPC ...
B01L 7/525 (2013.01); B01L 3/502792 (2013.01); B01L 2200/16 (2013.01); B01L 2300/0636 (2013.01); B01L 2300/0663 (2013.01); B01L 2300/1805 (2013.01);
Abstract

A method of thermal cycling a droplet, including providing a droplet actuator with heaters establishing a first thermal zone and second thermal zone in a substantially oil-filled droplet operations gap; a thermal cycling path comprising droplet operations electrodes comprising a first droplet operations electrode in the first thermal zone and a second droplet operations electrode in the second thermal zone, wherein the first and second droplet operations electrodes are within 5 mm of each other; a first temperature at the first droplet operations electrode and a second temperature at the second droplet operations electrode, wherein the first and second temperatures differ by at least about 10° C.; and using the droplet operations electrodes, transporting the droplet in a cycling pattern for multiple cycles along the thermal cycling path between the first droplet operations electrode and the second droplet operations electrode. Cartridges and systems are also provided.


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