The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 23, 2026
Filed:
Nov. 29, 2021
Methods and apparatus for modifying or killing cells by manipulating the cell membrane charging time
North Carolina State University, Raleigh, NC (US);
Michael Benjamin Sano, Cary, NC (US);
Christopher Fesmire, Cary, NC (US);
Ross A. Petrella, Richmond, VA (US);
NORTH CAROLINA STATE UNIVERSITY, Raleigh, NC (US);
Abstract
A method of treatment includes modifying and/or killing cells by changing the cell membrane charging time to make the cells more susceptible to the influence of electric fields. The method may further include inserting one or more electrodes into tissue, acquiring a temperature of the tissue, delivering electrical energy to the tissue by electrical pulses, determining a rate of energy delivery of the electrical energy such that the temperature rises above a first critical temperature but remains below a second critical temperature, and delivering the electrical energy until a specific dose is achieved.